If specific and functional kinase- or phosphatase-substrate interactions are optimized for binding compared to promiscuous interactions. then changes in phosphorylation should occur faster on functional versus promiscuous substrates. To test this hypothesis. we designed a high temporal resolution global phosphoproteomics protocol to study the high-osmolarity glycerol (HOG) response in... https://cosmeticssquadets.shop/product-category/spot-treatment/