The described method allows for detection of rare linear DNA fragments generated during genomic deletions. The predicted limit of the detection is one DNA molecule per 107 or more cells. The method is based on anchor PCR and involves gel separation of the linear DNA fragment and chromosomal DNA before amplification. https://www.diegojavierfares.com/quick-buy-Victorian-Dandy-Boys-Willy-Wonka-Book-Week-Costume-limited-save/